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Extract productive sequences from a RepSeqExperiment object by filtering out unproductive ones. Filtered sequences include:

- out-of-frame sequences: sequences with frame shifts based on the number of nucleotides in the ntCDR3 column.

- sequences containing stop codons: aaCDR3s with a "*" or "~" symbols.

Usage

getProductive(x)

Arguments

x

an object of class RepSeqExperiment.

Value

a filtered RepSeqExperiment object exclusively containing productive sequences.

Examples


data(RepSeqData)
productiveData <- getProductive(x = RepSeqData)