AnalyzAIRR - AIRR-compliant R package for the analysis of bulk Ig/TCR repertoire datasets

AnalyzAIRR is a AIRR-compliant R package developed to analyze bulk Ig/TCR repertoire datasets.

Details

AnalyzAIRR allows a general data exploration to evaluate the homogeneity within defined groups, identify outliers and filter them out. AnalyzAIRR also proposes a set of diversity measures and statistical metrics applicable at any level of granularity. Thus, single-sample repertoire explorations or in-depth cross-comparisons of AIRR datasets can be conducted leading to ready-to-publish visualization graphics. AnalyzAIRR is complemented with a guided workflow to help users in their analytical strategy, and a Shiny web application making it user-friendly for biologists with little or no background in bioinformatics.

See also

Useful links:

• https://github.com/i3-unit/AnalyzAIRR

• https://github.com/vanessajmh/Shiny-AnalyzAIRR

Author

• Vanessa Mhanna

• Gabriel Pires

• Grégoire Bohl

• Karim El Soufi

• Nicolas Tchitchek

• David Klatzmann

• Adrien Six

• Hang-Phuong Pham

• Encarnita Mariotti-Ferrandiz